- A new tripartite high level technical guidance harmonising the scientific and technical principles relevant to design, development and manufacture of drug substances as part of a total control strategy designed to ensure product quality and consistency.
- Harmonisation
- Facilitate innovative development over the product lifecycle in order to improve product and process understandin.
- no new regulatory requirements.
- Utility for regulators & industry.
- ICH Q7: Good Manufacturing Guides for Active Pharmaceutical Ingredients
- ICH Q11: Development and Manufacturer of Drug Substances
- Gap Analysis
- Advise and guidance on bridging the gap
- Documentation
- Supervising the compliance